Articles
  • Hydrolysis of Biopex-R-allografts cement and the osteoblastic response to the cement 
  • Takuya Nomoto, Shunro Yamaguchi*, Tohru Sekino and Koichi Niihara
  • Institute of Scientific and Industrial Research, Osaka University, Mihogaoka, Ibaraki, Osaka 567-0047, Japan
Abstract
A composite of clinically used Biopex-R and allografts was hydrolyzed in calf serum to obtain hydroxyapatite (HAP), while Biopex-R was hydrolyzed in calf serum to obtain octacalcium phosphate (OCP) and HAP. The products from Biopex-Rallografts composite as well as the Biopex-R exhibited rough surfaces. After the hydrolysis, MC3T3-E1 cells were cultured on the Biopex-R-allografts composite. Adherence of cells on Biopex-R-allografts composite is greater in number than on the Biopex-R. The composition of the resulting products affected the cell growth.

Keywords: calcium phosphate, bone cement, allograft, octacalcium phosphate, cell adhesion

This Article

  • 2004; 5(1): 76-79

    Published on Mar 31, 2004