Bioceramic hydroxyapatite (HAp) has excellent biocompatibility with bone tissue, and it exhibits good mechanical properties. We studied its mechanical properties and the effect on bone integration in a rabbit tibial defect model. HAp powder was prepared by spray drying and compression forming. The HAp powder sintered at 1350oC under a load of 1 tonne(9.8 KN) exhibited outstanding mechanical properties. In this test, the rabbit tibial defect was regenerated by using an HAp cylindrical implant.

Keywords: Hydroxyapatite, Spray dryer, Cylinder, Sintering, Implant.